Michel Schilperoord will present at the International Open Innovation conference (www.openinnovationtmc.org/) in Naples on the 27th of June 2018. He will provide input on development of a second pilot study for simulating and learning about the emergence of start-ups. In the first pilot study, set in the context of Irish High-Potential Start-ups Programme and published in 2016, a suite of simulation experiments was developed for testing predictors and policy with respect to high-potential start-ups. The outcomes of these experiments not only provided proof of concept for the predictors, but also confirmed the rationale for the HPSU Programme. The second pilot study will re-examine the outcomes of these experiments in the context of China’s move to mass entrepreneurship, with focus on the evolution of Shanghai’s start-up ecosystem.